Circle Us On Google Plus @ https://plus.google.com/+psychetruth Psychiatrist Tells the Truth About Clinical Trials | Science, Medicine, Psychiatry, Mental Health Psychetruth News Correspondent…
I completely agree. It is shocking how statistical data is manipulated by
Big Pharma in clinical trials – especially psychiatric trials. Even in
basic science, try to get a rebutal of ‘established theory’ published, the
peer reviewers don’t like negative data, it spoils the published ‘story’ –
and that’s all it is, a story, the way they would like biology to be, but
actually it isn’t! Such new data is commonly suppressed, or
published/hidden away in a much lower Impact Factor journal, which means
the original hypothesis essentially stands even you you have shown a
significant exception.
Don’t get me started on evidence based medicine. Did you know most
vaccines don’t work on most people. This is readily admitted on the vaccine
inserts themselves, believe it or not. For example, Flulaval Influenza
Virus Vaccine made by GlaxoSmithKline. This insert says, word for word:
“There have been no controlled trials adequately demonstrating a decrease
in influenza disease after vaccination with Flulaval.” (So much for
“evidence-based medicine.” Talk about a ‘shot’ in the dark!)
One of the big problems in designing drugs for multifactorial disease is
the approach taken by rational pharmacology to produce a drug that acts on
a specific biochemical pathway, whereas the disease is acting on several
diverse pathways. A good example, an anti-IL4 drug for asthma looked great
on paper, get it into clinical trials and it doesn’t do anything! Same for
SSRIs, they are too specific whereas depression isn’t specific- that’s why
natural compounds (with more than one active ingredient) such as rhodiola
rosea or St John’s wort are much more effective in treating such
conditions. At least SNRIs are a step in the right direction. But at the
end of the day it’s your attitude that counts the drugs can act as a safety
net but the individual must learn to ‘catch’ the negative thoughts that
lead them over a cliff into clinical depression and hence allow those
neural circuit(s) to disperse. Hence we need to switch our view from the
analytical to the synthetic – dare I say holistic.
So true! Psychiatry is a bad joke. The whole basis of many drugs e.g.
SSRIs, SNRIs etc.(that low serotonin causes depression) is just Pharma BS
to sell the drugs. The fact that antidepressants and many other drugs have
little or no demonstrated benefit beyond the placebo effect is a good
example of the failing of these incestuous corporate-controlled
“researchers”. Almost all the drugs for many conditions are not shown to
work by any research even close to reliable… tier 2 quality at best.
Studies get done to get the money (tenure, grants, Pharma payoffs etc) but
they are trash, worthless, usually because they have not bothered to
control the variables and the placebo well enough.
It depends on the trial is, some of these clinical trials deal with
“psilocybin” that deals with migraine headaches, depression, PTSD, and
other problems that people have. The first people from the first trials
about migraines and the doctors followed up with these people and found
that these people haven’t a headache in 31/2 years!!!
What money does, how it works.
You can talk about the problem and never get to the solution, forever!
How about prevention? How about never having to deal with these diseases
that have been around for a very long time now, collecting money by the
billions to “study” …who would not be in business long if they actually
found a cure. And is this okay? Really? We would straightaway get to the
solution if we did not have to deal with the incentives and manipulations
behind money that infect everything, or deal with money, period would be
even better. It’s got us behaving and living in unnatural ways =
unnecessary stress and frustration.
It doesn’t matter what issue you discuss, when you run into money, there is
the real problem underlying ALL PROBLEMS WE FACE. Money is the reason for
the problem + it is the reason we can solve none of them. Until we just
get back to our hearts, give and receive according to common sense, and our
innate Intelligence, this will go on and on and humanity will suffer
greatly because of it.
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I completely agree. It is shocking how statistical data is manipulated by
Big Pharma in clinical trials – especially psychiatric trials. Even in
basic science, try to get a rebutal of ‘established theory’ published, the
peer reviewers don’t like negative data, it spoils the published ‘story’ –
and that’s all it is, a story, the way they would like biology to be, but
actually it isn’t! Such new data is commonly suppressed, or
published/hidden away in a much lower Impact Factor journal, which means
the original hypothesis essentially stands even you you have shown a
significant exception.
Don’t get me started on evidence based medicine. Did you know most
vaccines don’t work on most people. This is readily admitted on the vaccine
inserts themselves, believe it or not. For example, Flulaval Influenza
Virus Vaccine made by GlaxoSmithKline. This insert says, word for word:
“There have been no controlled trials adequately demonstrating a decrease
in influenza disease after vaccination with Flulaval.” (So much for
“evidence-based medicine.” Talk about a ‘shot’ in the dark!)
One of the big problems in designing drugs for multifactorial disease is
the approach taken by rational pharmacology to produce a drug that acts on
a specific biochemical pathway, whereas the disease is acting on several
diverse pathways. A good example, an anti-IL4 drug for asthma looked great
on paper, get it into clinical trials and it doesn’t do anything! Same for
SSRIs, they are too specific whereas depression isn’t specific- that’s why
natural compounds (with more than one active ingredient) such as rhodiola
rosea or St John’s wort are much more effective in treating such
conditions. At least SNRIs are a step in the right direction. But at the
end of the day it’s your attitude that counts the drugs can act as a safety
net but the individual must learn to ‘catch’ the negative thoughts that
lead them over a cliff into clinical depression and hence allow those
neural circuit(s) to disperse. Hence we need to switch our view from the
analytical to the synthetic – dare I say holistic.
So true! Psychiatry is a bad joke. The whole basis of many drugs e.g.
SSRIs, SNRIs etc.(that low serotonin causes depression) is just Pharma BS
to sell the drugs. The fact that antidepressants and many other drugs have
little or no demonstrated benefit beyond the placebo effect is a good
example of the failing of these incestuous corporate-controlled
“researchers”. Almost all the drugs for many conditions are not shown to
work by any research even close to reliable… tier 2 quality at best.
Studies get done to get the money (tenure, grants, Pharma payoffs etc) but
they are trash, worthless, usually because they have not bothered to
control the variables and the placebo well enough.
Nice to see a real Psychiatrist/Scientist explain the Peer Review process.
It depends on the trial is, some of these clinical trials deal with
“psilocybin” that deals with migraine headaches, depression, PTSD, and
other problems that people have. The first people from the first trials
about migraines and the doctors followed up with these people and found
that these people haven’t a headache in 31/2 years!!!
do you enjoy your talks with the shrink-
What money does, how it works.
You can talk about the problem and never get to the solution, forever!
How about prevention? How about never having to deal with these diseases
that have been around for a very long time now, collecting money by the
billions to “study” …who would not be in business long if they actually
found a cure. And is this okay? Really? We would straightaway get to the
solution if we did not have to deal with the incentives and manipulations
behind money that infect everything, or deal with money, period would be
even better. It’s got us behaving and living in unnatural ways =
unnecessary stress and frustration.
It doesn’t matter what issue you discuss, when you run into money, there is
the real problem underlying ALL PROBLEMS WE FACE. Money is the reason for
the problem + it is the reason we can solve none of them. Until we just
get back to our hearts, give and receive according to common sense, and our
innate Intelligence, this will go on and on and humanity will suffer
greatly because of it.
Is research and development an on going thing with each individual patient
and the study in real time?
Dr ross was on that jesse ventura show a whileback